| 21 de fev.16:30 |  St.Louis City× Charlotte FC | |  Charlotte FC |
| 21 de fev.18:45 |  FC Cincinnati× Atlanta United | |  Atlanta United |
| 21 de fev.21:30 |  Orlando City SC× New York Red Bulls | |  New York Red Bulls |
| 21 de fev.21:30 |  Vancouver Whitecaps× Real Salt Lake | |  Real Salt Lake |
| 21 de fev.21:30 |  DC United× Philadelphia Union | |  Philadelphia Union |
| 21 de fev.22:30 |  FC Dallas× Toronto FC | |  Toronto FC |
| 21 de fev.22:30 |  Austin FC× Minnesota United | |  Minnesota United |
| 21 de fev.22:30 |  Nashville SC× New England Revolution | |  New England Revolution |
| 21 de fev.22:30 |  Houston Dynamo× Chicago Fire | |  Chicago Fire |
| 21 de fev.23:30 |  Los Angeles FC× Inter Miami CF | |  Inter Miami CF |
| 22 de fev.00:30 |  San Jose Earthquakes× Sporting Kansas City | |  Sporting Kansas City |
| 22 de fev.00:30 |  Portland Timbers× Columbus Crew | |  Columbus Crew |
| 22 de fev.00:30 |  San Diego FC× CF Montréal | |  CF Montréal |
| 22 de fev.21:00 |  LA Galaxy× New York City FC | |  New York City FC |
| 22 de fev.23:15 |  Seattle Sounders FC× Colorado Rapids | |  Colorado Rapids |
| 28 de fev.16:30 | New York Red Bulls× New England Revolution | | New England Revolution |
| 28 de fev.16:30 | Chicago Fire× CF Montréal | | CF Montréal |
| 28 de fev.18:30 | Minnesota United× FC Cincinnati | | FC Cincinnati |
| 28 de fev.18:30 | Colorado Rapids× Portland Timbers | | Portland Timbers |
| 28 de fev.21:30 | San Jose Earthquakes× Atlanta United | | Atlanta United |
| 28 de fev.21:30 | Real Salt Lake× Seattle Sounders FC | | Seattle Sounders FC |
| 28 de fev.22:30 | Sporting Kansas City× Columbus Crew | | Columbus Crew |
| 28 de fev.22:30 | Houston Dynamo× Los Angeles FC | | Los Angeles FC |
| 28 de fev.22:30 | FC Dallas× Nashville SC | | Nashville SC |
| 28 de fev.23:30 | Vancouver Whitecaps× Toronto FC | | Toronto FC |
| 01 de mar.00:30 | LA Galaxy× Charlotte FC | | Charlotte FC |
| 01 de mar.16:30 | Austin FC× DC United | | DC United |
| 01 de mar.18:30 | Philadelphia Union× New York City FC | | New York City FC |
| 01 de mar.21:00 | Orlando City SC× Inter Miami CF | | Inter Miami CF |
| 01 de mar.23:15 | San Diego FC× St.Louis City | | St.Louis City |
| 07 de mar.16:30 | New York City FC× Orlando City SC | | Orlando City SC |
| 07 de mar.18:30 | DC United× Inter Miami CF | | Inter Miami CF |
| 07 de mar.21:30 | Columbus Crew× Chicago Fire | | Chicago Fire |
| 07 de mar.21:30 | Philadelphia Union× San Jose Earthquakes | | San Jose Earthquakes |
| 07 de mar.21:30 | Atlanta United× Real Salt Lake | | Real Salt Lake |
| 07 de mar.21:30 | Charlotte FC× Austin FC | | Austin FC |
| 07 de mar.22:30 | Nashville SC× Minnesota United | | Minnesota United |
| 07 de mar.22:30 | St.Louis City× Seattle Sounders FC | | Seattle Sounders FC |
| 07 de mar.22:30 | Sporting Kansas City× San Diego FC | | San Diego FC |
| 07 de mar.23:30 | Colorado Rapids× LA Galaxy | | LA Galaxy |
| 08 de mar.00:30 | Los Angeles FC× FC Dallas | | FC Dallas |
| 08 de mar.00:30 | Portland Timbers× Vancouver Whitecaps | | Vancouver Whitecaps |
| 08 de mar.17:30 | New York Red Bulls× CF Montréal | | CF Montréal |
| 08 de mar.20:00 | FC Cincinnati× Toronto FC | | Toronto FC |
| 14 de mar.14:00 | Toronto FC× New York Red Bulls | | New York Red Bulls |
| 14 de mar.16:15 | Atlanta United× Philadelphia Union | | Philadelphia Union |
| 14 de mar.19:15 | Columbus Crew× Nashville SC | | Nashville SC |
| 14 de mar.20:30 | Charlotte FC× Inter Miami CF | | Inter Miami CF |
| 14 de mar.20:30 | New York City FC× Colorado Rapids | | Colorado Rapids |
| 14 de mar.20:30 | Orlando City SC× CF Montréal | | CF Montréal |
| 14 de mar.21:30 | FC Dallas× San Diego FC | | San Diego FC |
| 14 de mar.21:30 | Chicago Fire× DC United | | DC United |
| 14 de mar.21:30 | Houston Dynamo× Portland Timbers | | Portland Timbers |
| 14 de mar.22:30 | Real Salt Lake× Austin FC | | Austin FC |
| 14 de mar.22:30 | LA Galaxy× Sporting Kansas City | | Sporting Kansas City |
| 14 de mar.23:30 | Los Angeles FC× St.Louis City | | St.Louis City |
| 15 de mar.15:30 | New England Revolution× FC Cincinnati | | FC Cincinnati |
| 15 de mar.17:30 | Vancouver Whitecaps× Minnesota United | | Minnesota United |
| 15 de mar.20:00 | San Jose Earthquakes× Seattle Sounders FC | | Seattle Sounders FC |
| 21 de mar.14:00 | Toronto FC× Columbus Crew | | Columbus Crew |
| 21 de mar.17:30 | Philadelphia Union× Chicago Fire | | Chicago Fire |
| 21 de mar.19:15 | Nashville SC× Orlando City SC | | Orlando City SC |
| 21 de mar.20:30 | Charlotte FC× New York Red Bulls | | New York Red Bulls |
| 21 de mar.20:30 | Atlanta United× DC United | | DC United |
| 21 de mar.21:30 | FC Dallas× Houston Dynamo | | Houston Dynamo |
| 21 de mar.21:30 | Sporting Kansas City× Colorado Rapids | | Colorado Rapids |
| 21 de mar.21:30 | St.Louis City× New England Revolution | | New England Revolution |
| 21 de mar.21:45 | Austin FC× Los Angeles FC | | Los Angeles FC |
| 21 de mar.23:30 | Vancouver Whitecaps× San Jose Earthquakes | | San Jose Earthquakes |
| 22 de mar.14:00 | FC Cincinnati× CF Montréal | | CF Montréal |
| 22 de mar.14:00 | New York City FC× Inter Miami CF | | Inter Miami CF |
| 22 de mar.15:30 | Minnesota United× Seattle Sounders FC | | Seattle Sounders FC |
| 22 de mar.17:45 | Portland Timbers× LA Galaxy | | LA Galaxy |
| 22 de mar.20:00 | San Diego FC× Real Salt Lake | | Real Salt Lake |
| 04 de abr.14:00 | Toronto FC× Colorado Rapids | | Colorado Rapids |
| 04 de abr.17:30 | New England Revolution× CF Montréal | | CF Montréal |
| 04 de abr.17:30 | Real Salt Lake× Sporting Kansas City | | Sporting Kansas City |
| 04 de abr.20:30 | Atlanta United× Columbus Crew | | Columbus Crew |
| 04 de abr.20:30 | New York Red Bulls× FC Cincinnati | | FC Cincinnati |
| 04 de abr.20:30 | Charlotte FC× Philadelphia Union | | Philadelphia Union |
| 04 de abr.20:30 | New York City FC× St.Louis City | | St.Louis City |
| 04 de abr.20:30 | DC United× FC Dallas | | FC Dallas |
| 04 de abr.20:45 | Inter Miami CF× Austin FC | | Austin FC |
| 04 de abr.21:30 | Chicago Fire× Nashville SC | | Nashville SC |
| 04 de abr.22:00 | Houston Dynamo× Seattle Sounders FC | | Seattle Sounders FC |
| 04 de abr.22:30 | Los Angeles FC× Orlando City SC | | Orlando City SC |
| 04 de abr.23:30 | LA Galaxy× Minnesota United | | Minnesota United |
| 04 de abr.23:30 | San Jose Earthquakes× San Diego FC | | San Diego FC |
| 04 de abr.23:30 | Vancouver Whitecaps× Portland Timbers | | Portland Timbers |
| 11 de abr.14:00 | Toronto FC× FC Cincinnati | | FC Cincinnati |
| 11 de abr.15:30 | Austin FC× LA Galaxy | | LA Galaxy |
| 11 de abr.15:30 | CF Montréal× Philadelphia Union | | Philadelphia Union |
| 11 de abr.17:45 | Portland Timbers× Los Angeles FC | | Los Angeles FC |
| 11 de abr.20:30 | New England Revolution× DC United | | DC United |
| 11 de abr.20:30 | Inter Miami CF× New York Red Bulls | | New York Red Bulls |
| 11 de abr.20:30 | Vancouver Whitecaps× New York City FC | | New York City FC |
| 11 de abr.20:30 | Charlotte FC× Nashville SC | | Nashville SC |
| 11 de abr.21:30 | Chicago Fire× Atlanta United | | Atlanta United |
| 11 de abr.21:30 | Sporting Kansas City× San Jose Earthquakes | | San Jose Earthquakes |
| 11 de abr.21:30 | FC Dallas× St.Louis City | | St.Louis City |
| 11 de abr.22:30 | Colorado Rapids× Houston Dynamo | | Houston Dynamo |
| 11 de abr.23:30 | San Diego FC× Minnesota United | | Minnesota United |
| 12 de abr.20:00 | Columbus Crew× Orlando City SC | | Orlando City SC |
| 17 de abr.23:30 | Vancouver Whitecaps× Sporting Kansas City | | Sporting Kansas City |
| 18 de abr.14:00 | Toronto FC× Austin FC | | Austin FC |
| 18 de abr.15:30 | CF Montréal× New York Red Bulls | | New York Red Bulls |
| 18 de abr.17:30 | Colorado Rapids× Inter Miami CF | | Inter Miami CF |
| 18 de abr.20:30 | Atlanta United× Nashville SC | | Nashville SC |
| 18 de abr.20:30 | FC Cincinnati× Chicago Fire | | Chicago Fire |
| 18 de abr.20:30 | New England Revolution× Columbus Crew | | Columbus Crew |
| 18 de abr.20:30 | New York City FC× Charlotte FC | | Charlotte FC |
| 18 de abr.20:30 | Philadelphia Union× DC United | | DC United |
| 18 de abr.20:30 | Orlando City SC× Houston Dynamo | | Houston Dynamo |
| 18 de abr.21:30 | FC Dallas× LA Galaxy | | LA Galaxy |
| 18 de abr.21:30 | Minnesota United× Portland Timbers | | Portland Timbers |
| 18 de abr.22:30 | Seattle Sounders FC× St.Louis City | | St.Louis City |
| 18 de abr.22:30 | Real Salt Lake× San Diego FC | | San Diego FC |
| 19 de abr.20:00 | Los Angeles FC× San Jose Earthquakes | | San Jose Earthquakes |
| 22 de abr.20:30 | Columbus Crew× LA Galaxy | | LA Galaxy |
| 22 de abr.20:30 | New York City FC× FC Cincinnati | | FC Cincinnati |
| 22 de abr.20:30 | Toronto FC× Philadelphia Union | | Philadelphia Union |
| 22 de abr.20:30 | New York Red Bulls× DC United | | DC United |
| 22 de abr.20:30 | Orlando City SC× Charlotte FC | | Charlotte FC |
| 22 de abr.20:45 | Atlanta United× New England Revolution | | New England Revolution |
| 22 de abr.21:30 | FC Dallas× Minnesota United | | Minnesota United |
| 22 de abr.21:30 | Houston Dynamo× San Diego FC | | San Diego FC |
| 22 de abr.22:30 | Real Salt Lake× Inter Miami CF | | Inter Miami CF |
| 22 de abr.23:30 | San Jose Earthquakes× Austin FC | | Austin FC |
| 22 de abr.23:30 | Los Angeles FC× Colorado Rapids | | Colorado Rapids |
| 25 de abr.14:00 | Toronto FC× Atlanta United | | Atlanta United |
| 25 de abr.15:30 | CF Montréal× New York City FC | | New York City FC |
| 25 de abr.17:45 | Minnesota United× Los Angeles FC | | Los Angeles FC |
| 25 de abr.20:30 | Inter Miami CF× New England Revolution | | New England Revolution |
| 25 de abr.20:30 | FC Cincinnati× New York Red Bulls | | New York Red Bulls |
| 25 de abr.20:30 | DC United× Orlando City SC | | Orlando City SC |
| 25 de abr.20:30 | Columbus Crew× Philadelphia Union | | Philadelphia Union |
| 25 de abr.21:30 | Nashville SC× Charlotte FC | | Charlotte FC |
| 25 de abr.21:30 | Chicago Fire× Sporting Kansas City | | Sporting Kansas City |
| 25 de abr.21:30 | Austin FC× Houston Dynamo | | Houston Dynamo |
| 25 de abr.21:30 | St.Louis City× San Jose Earthquakes | | San Jose Earthquakes |
| 25 de abr.22:30 | San Diego FC× Portland Timbers | | Portland Timbers |
| 25 de abr.23:30 | Vancouver Whitecaps× Colorado Rapids | | Colorado Rapids |
| 25 de abr.23:30 | Seattle Sounders FC× FC Dallas | | FC Dallas |
| 26 de abr.20:00 | LA Galaxy× Real Salt Lake | | Real Salt Lake |
| 02 de mai.14:00 | Toronto FC× San Jose Earthquakes | | San Jose Earthquakes |
| 02 de mai.15:30 | Sporting Kansas City× Seattle Sounders FC | | Seattle Sounders FC |
| 02 de mai.17:45 | Real Salt Lake× Portland Timbers | | Portland Timbers |
| 02 de mai.20:15 | Inter Miami CF× Orlando City SC | | Orlando City SC |
| 02 de mai.20:30 | Philadelphia Union× Nashville SC | | Nashville SC |
| 02 de mai.20:30 | Atlanta United× CF Montréal | | CF Montréal |
| 02 de mai.20:30 | New York Red Bulls× FC Dallas | | FC Dallas |
| 02 de mai.20:30 | New England Revolution× Charlotte FC | | Charlotte FC |
| 02 de mai.20:30 | Columbus Crew× Minnesota United | | Minnesota United |
| 02 de mai.21:30 | Chicago Fire× FC Cincinnati | | FC Cincinnati |
| 02 de mai.21:30 | Houston Dynamo× Colorado Rapids | | Colorado Rapids |
| 02 de mai.22:30 | San Diego FC× Los Angeles FC | | Los Angeles FC |
| 02 de mai.23:30 | LA Galaxy× Vancouver Whitecaps | | Vancouver Whitecaps |
| 03 de mai.16:00 | New York City FC× DC United | | DC United |
| 03 de mai.18:30 | Austin FC× St.Louis City | | St.Louis City |
| 09 de mai.14:00 | Toronto FC× Inter Miami CF | | Inter Miami CF |
| 09 de mai.15:30 | Chicago Fire× New York Red Bulls | | New York Red Bulls |
| 09 de mai.17:30 | CF Montréal× Orlando City SC | | Orlando City SC |
| 09 de mai.20:30 | Atlanta United× LA Galaxy | | LA Galaxy |
| 09 de mai.20:30 | Charlotte FC× FC Cincinnati | | FC Cincinnati |
| 09 de mai.20:30 | New England Revolution× Philadelphia Union | | Philadelphia Union |
| 09 de mai.21:30 | FC Dallas× Real Salt Lake | | Real Salt Lake |
| 09 de mai.22:15 | Nashville SC× DC United | | DC United |
| 09 de mai.22:30 | Colorado Rapids× St.Louis City | | St.Louis City |
| 09 de mai.23:30 | Seattle Sounders FC× San Diego FC | | San Diego FC |
| 09 de mai.23:30 | San Jose Earthquakes× Vancouver Whitecaps | | Vancouver Whitecaps |
| 09 de mai.23:30 | Portland Timbers× Sporting Kansas City | | Sporting Kansas City |
| 10 de mai.17:30 | New York City FC× Columbus Crew | | Columbus Crew |
| 10 de mai.20:00 | Minnesota United× Austin FC | | Austin FC |
| 10 de mai.22:00 | Los Angeles FC× Houston Dynamo | | Houston Dynamo |
| 13 de mai.20:15 | Charlotte FC× New York City FC | | New York City FC |
| 13 de mai.20:30 | FC Cincinnati× Inter Miami CF | | Inter Miami CF |
| 13 de mai.20:30 | New York Red Bulls× Columbus Crew | | Columbus Crew |
| 13 de mai.20:30 | New England Revolution× Nashville SC | | Nashville SC |
| 13 de mai.20:30 | DC United× Chicago Fire | | Chicago Fire |
| 13 de mai.20:30 | CF Montréal× Portland Timbers | | Portland Timbers |
| 13 de mai.20:30 | Orlando City SC× Philadelphia Union | | Philadelphia Union |
| 13 de mai.21:30 | FC Dallas× Vancouver Whitecaps | | Vancouver Whitecaps |
| 13 de mai.21:30 | Sporting Kansas City× LA Galaxy | | LA Galaxy |
| 13 de mai.21:30 | Minnesota United× Colorado Rapids | | Colorado Rapids |
| 13 de mai.21:30 | St.Louis City× Los Angeles FC | | Los Angeles FC |
| 13 de mai.22:30 | Seattle Sounders FC× San Jose Earthquakes | | San Jose Earthquakes |
| 13 de mai.22:30 | Real Salt Lake× Houston Dynamo | | Houston Dynamo |
| 13 de mai.22:30 | San Diego FC× Austin FC | | Austin FC |
| 16 de mai.17:30 | CF Montréal× Chicago Fire | | Chicago Fire |
| 16 de mai.20:30 | Orlando City SC× Atlanta United | | Atlanta United |
| 16 de mai.20:30 | New England Revolution× Minnesota United | | Minnesota United |
| 16 de mai.20:30 | New York Red Bulls× New York City FC | | New York City FC |
| 16 de mai.20:30 | Philadelphia Union× Columbus Crew | | Columbus Crew |
| 16 de mai.20:30 | DC United× St.Louis City | | St.Louis City |
| 16 de mai.20:30 | Charlotte FC× Toronto FC | | Toronto FC |
| 16 de mai.21:30 | Austin FC× Sporting Kansas City | | Sporting Kansas City |
| 16 de mai.21:30 | Houston Dynamo× Vancouver Whitecaps | | Vancouver Whitecaps |
| 16 de mai.22:15 | Seattle Sounders FC× LA Galaxy | | LA Galaxy |
| 16 de mai.22:30 | San Diego FC× FC Cincinnati | | FC Cincinnati |
| 16 de mai.22:30 | Real Salt Lake× Colorado Rapids | | Colorado Rapids |
| 16 de mai.23:30 | San Jose Earthquakes× FC Dallas | | FC Dallas |
| 17 de mai.19:00 | Inter Miami CF× Portland Timbers | | Portland Timbers |
| 17 de mai.21:00 | Nashville SC× Los Angeles FC | | Los Angeles FC |
| 23 de mai.15:45 | St.Louis City× Austin FC | | Austin FC |
| 23 de mai.17:30 | Minnesota United× Real Salt Lake | | Real Salt Lake |
| 23 de mai.20:30 | Charlotte FC× New England Revolution | | New England Revolution |
| 23 de mai.20:30 | DC United× CF Montréal | | CF Montréal |
| 23 de mai.20:30 | FC Cincinnati× Orlando City SC | | Orlando City SC |
| 23 de mai.21:30 | Nashville SC× New York City FC | | New York City FC |
| 23 de mai.21:30 | Chicago Fire× Toronto FC | | Toronto FC |
| 23 de mai.21:30 | Sporting Kansas City× New York Red Bulls | | New York Red Bulls |
| 23 de mai.22:30 | Portland Timbers× San Jose Earthquakes | | San Jose Earthquakes |
| 23 de mai.22:30 | Colorado Rapids× FC Dallas | | FC Dallas |
| 23 de mai.22:30 | San Diego FC× Vancouver Whitecaps | | Vancouver Whitecaps |
| 23 de mai.23:30 | LA Galaxy× Houston Dynamo | | Houston Dynamo |
| 24 de mai.18:00 | Columbus Crew× Atlanta United | | Atlanta United |
| 24 de mai.20:00 | Inter Miami CF× Philadelphia Union | | Philadelphia Union |
| 24 de mai.22:25 | Los Angeles FC× Seattle Sounders FC | | Seattle Sounders FC |
| 16 de jul.20:30 | CF Montréal× Toronto FC | | Toronto FC |
| 16 de jul.21:30 | St.Louis City× Sporting Kansas City | | Sporting Kansas City |
| 16 de jul.23:30 | Seattle Sounders FC× Portland Timbers | | Portland Timbers |
| 17 de jul.21:10 | Nashville SC× Atlanta United | | Atlanta United |
| 17 de jul.23:25 | LA Galaxy× Los Angeles FC | | Los Angeles FC |
| 22 de jul.20:30 | Columbus Crew× New York City FC | | New York City FC |
| 22 de jul.20:30 | FC Cincinnati× Vancouver Whitecaps | | Vancouver Whitecaps |
| 22 de jul.20:30 | Inter Miami CF× Chicago Fire | | Chicago Fire |
| 22 de jul.20:30 | New England Revolution× Toronto FC | | Toronto FC |
| 22 de jul.20:30 | Philadelphia Union× New York Red Bulls | | New York Red Bulls |
| 22 de jul.21:15 | Charlotte FC× Atlanta United | | Atlanta United |
| 22 de jul.21:30 | Houston Dynamo× DC United | | DC United |
| 22 de jul.21:30 | Nashville SC× CF Montréal | | CF Montréal |
| 22 de jul.21:30 | Sporting Kansas City× Minnesota United | | Minnesota United |
| 22 de jul.22:30 | Austin FC× Seattle Sounders FC | | Seattle Sounders FC |
| 22 de jul.22:30 | Colorado Rapids× San Diego FC | | San Diego FC |
| 22 de jul.23:30 | LA Galaxy× St.Louis City | | St.Louis City |
| 22 de jul.23:30 | Los Angeles FC× Real Salt Lake | | Real Salt Lake |
| 22 de jul.23:30 | Portland Timbers× FC Dallas | | FC Dallas |
| 22 de jul.23:30 | San Jose Earthquakes× Orlando City SC | | Orlando City SC |
| 25 de jul.19:30 | New York Red Bulls× Charlotte FC | | Charlotte FC |
| 25 de jul.20:15 | Columbus Crew× FC Cincinnati | | FC Cincinnati |
| 25 de jul.20:30 | CF Montréal× Inter Miami CF | | Inter Miami CF |
| 25 de jul.20:30 | DC United× Toronto FC | | Toronto FC |
| 25 de jul.20:30 | New England Revolution× Atlanta United | | Atlanta United |
| 25 de jul.20:30 | New York City FC× Chicago Fire | | Chicago Fire |
| 25 de jul.20:30 | Philadelphia Union× Seattle Sounders FC | | Seattle Sounders FC |
| 25 de jul.21:30 | Houston Dynamo× Austin FC | | Austin FC |
| 25 de jul.21:30 | Minnesota United× Vancouver Whitecaps | | Vancouver Whitecaps |
| 25 de jul.21:30 | St.Louis City× Colorado Rapids | | Colorado Rapids |
| 25 de jul.21:46 | Orlando City SC× Nashville SC | | Nashville SC |
| 25 de jul.22:30 | San Diego FC× FC Dallas | | FC Dallas |
| 25 de jul.23:30 | Los Angeles FC× Sporting Kansas City | | Sporting Kansas City |
| 25 de jul.23:30 | Portland Timbers× Real Salt Lake | | Real Salt Lake |
| 25 de jul.23:30 | San Jose Earthquakes× LA Galaxy | | LA Galaxy |
| 31 de jul.20:30 | New York City FC× Toronto FC | | Toronto FC |
| 01 de ago.20:30 | CF Montréal× New England Revolution | | New England Revolution |
| 01 de ago.20:30 | DC United× Nashville SC | | Nashville SC |
| 01 de ago.20:30 | New York Red Bulls× Orlando City SC | | Orlando City SC |
| 01 de ago.20:30 | Philadelphia Union× Atlanta United | | Atlanta United |
| 01 de ago.20:30 | Vancouver Whitecaps× Los Angeles FC | | Los Angeles FC |
| 01 de ago.21:10 | Inter Miami CF× Columbus Crew | | Columbus Crew |
| 01 de ago.21:30 | Sporting Kansas City× Houston Dynamo | | Houston Dynamo |
| 01 de ago.21:30 | Chicago Fire× Charlotte FC | | Charlotte FC |
| 01 de ago.21:30 | Minnesota United× San Diego FC | | San Diego FC |
| 01 de ago.21:30 | St.Louis City× Real Salt Lake | | Real Salt Lake |
| 01 de ago.22:30 | Colorado Rapids× Austin FC | | Austin FC |
| 01 de ago.22:45 | FC Cincinnati× San Jose Earthquakes | | San Jose Earthquakes |
| 01 de ago.23:30 | LA Galaxy× FC Dallas | | FC Dallas |
| 01 de ago.23:45 | Portland Timbers× Seattle Sounders FC | | Seattle Sounders FC |
| 08 de ago.17:30 | New England Revolution× Houston Dynamo | | Houston Dynamo |
| 15 de ago.20:30 | Toronto FC× New England Revolution | | New England Revolution |
| 15 de ago.20:30 | Orlando City SC× FC Cincinnati | | FC Cincinnati |
| 15 de ago.20:30 | Atlanta United× New York Red Bulls | | New York Red Bulls |
| 15 de ago.20:30 | CF Montréal× DC United | | DC United |
| 15 de ago.20:30 | Charlotte FC× Columbus Crew | | Columbus Crew |
| 15 de ago.21:30 | Houston Dynamo× LA Galaxy | | LA Galaxy |
| 15 de ago.21:30 | Nashville SC× Inter Miami CF | | Inter Miami CF |
| 15 de ago.22:30 | Colorado Rapids× Sporting Kansas City | | Sporting Kansas City |
| 15 de ago.22:30 | Real Salt Lake× Minnesota United | | Minnesota United |
| 15 de ago.23:30 | San Jose Earthquakes× St.Louis City | | St.Louis City |
| 15 de ago.23:30 | Los Angeles FC× San Diego FC | | San Diego FC |
| 16 de ago.19:00 | New York City FC× Philadelphia Union | | Philadelphia Union |
| 16 de ago.19:00 | Chicago Fire× Portland Timbers | | Portland Timbers |
| 16 de ago.21:30 | Austin FC× FC Dallas | | FC Dallas |
| 16 de ago.23:30 | Seattle Sounders FC× Vancouver Whitecaps | | Vancouver Whitecaps |
| 19 de ago.20:30 | Columbus Crew× CF Montréal | | CF Montréal |
| 19 de ago.20:30 | DC United× New England Revolution | | New England Revolution |
| 19 de ago.20:30 | FC Cincinnati× New York City FC | | New York City FC |
| 19 de ago.20:30 | New York Red Bulls× Nashville SC | | Nashville SC |
| 19 de ago.20:30 | Toronto FC× Charlotte FC | | Charlotte FC |
| 19 de ago.20:30 | Philadelphia Union× Inter Miami CF | | Inter Miami CF |
| 19 de ago.20:30 | Orlando City SC× Chicago Fire | | Chicago Fire |
| 19 de ago.21:00 | Sporting Kansas City× St.Louis City | | St.Louis City |
| 19 de ago.21:30 | Minnesota United× Atlanta United | | Atlanta United |
| 19 de ago.22:30 | Colorado Rapids× Los Angeles FC | | Los Angeles FC |
| 19 de ago.22:30 | Real Salt Lake× FC Dallas | | FC Dallas |
| 19 de ago.22:30 | Seattle Sounders FC× Austin FC | | Austin FC |
| 19 de ago.23:30 | LA Galaxy× San Jose Earthquakes | | San Jose Earthquakes |
| 19 de ago.23:30 | Portland Timbers× San Diego FC | | San Diego FC |
| 19 de ago.23:30 | Vancouver Whitecaps× Houston Dynamo | | Houston Dynamo |
| 22 de ago.20:30 | CF Montréal× LA Galaxy | | LA Galaxy |
| 22 de ago.20:30 | New York Red Bulls× Chicago Fire | | Chicago Fire |
| 22 de ago.20:30 | Orlando City SC× Real Salt Lake | | Real Salt Lake |
| 22 de ago.20:30 | Charlotte FC× DC United | | DC United |
| 22 de ago.20:30 | FC Cincinnati× Seattle Sounders FC | | Seattle Sounders FC |
| 22 de ago.20:30 | Inter Miami CF× Toronto FC | | Toronto FC |
| 22 de ago.21:30 | St.Louis City× Houston Dynamo | | Houston Dynamo |
| 22 de ago.21:30 | Nashville SC× Columbus Crew | | Columbus Crew |
| 22 de ago.22:00 | Austin FC× Philadelphia Union | | Philadelphia Union |
| 22 de ago.22:30 | Vancouver Whitecaps× FC Dallas | | FC Dallas |
| 22 de ago.23:30 | Los Angeles FC× Portland Timbers | | Portland Timbers |
| 22 de ago.23:30 | San Diego FC× Colorado Rapids | | Colorado Rapids |
| 22 de ago.23:30 | San Jose Earthquakes× Minnesota United | | Minnesota United |
| 23 de ago.17:30 | New England Revolution× New York City FC | | New York City FC |
| 23 de ago.20:00 | Atlanta United× Sporting Kansas City | | Sporting Kansas City |
| 29 de ago.17:30 | Seattle Sounders FC× Chicago Fire | | Chicago Fire |
| 29 de ago.20:30 | Atlanta United× Charlotte FC | | Charlotte FC |
| 29 de ago.20:30 | DC United× Los Angeles FC | | Los Angeles FC |
| 29 de ago.20:30 | New York Red Bulls× Philadelphia Union | | Philadelphia Union |
| 29 de ago.20:30 | Toronto FC× New York City FC | | New York City FC |
| 29 de ago.20:30 | Inter Miami CF× CF Montréal | | CF Montréal |
| 29 de ago.21:30 | Minnesota United× Orlando City SC | | Orlando City SC |
| 29 de ago.21:30 | Nashville SC× FC Cincinnati | | FC Cincinnati |
| 29 de ago.21:30 | Sporting Kansas City× Vancouver Whitecaps | | Vancouver Whitecaps |
| 29 de ago.21:30 | Houston Dynamo× San Jose Earthquakes | | San Jose Earthquakes |
| 29 de ago.22:30 | Colorado Rapids× Real Salt Lake | | Real Salt Lake |
| 29 de ago.23:30 | Portland Timbers× Austin FC | | Austin FC |
| 29 de ago.23:30 | San Diego FC× LA Galaxy | | LA Galaxy |
| 30 de ago.17:30 | Columbus Crew× New England Revolution | | New England Revolution |
| 30 de ago.20:00 | St.Louis City× FC Dallas | | FC Dallas |
| 04 de set.20:30 | New York City FC× Nashville SC | | Nashville SC |
| 05 de set.20:30 | FC Cincinnati× DC United | vs | DC United |
| 05 de set.20:30 | Inter Miami CF× Atlanta United | vs | Atlanta United |
| 05 de set.20:30 | Orlando City SC× San Diego FC | vs | San Diego FC |
| 05 de set.20:30 | Philadelphia Union× CF Montréal | vs | CF Montréal |
| 05 de set.20:30 | Toronto FC× Chicago Fire | vs | Chicago Fire |
| 05 de set.20:30 | Charlotte FC× Houston Dynamo | vs | Houston Dynamo |
| 05 de set.20:30 | Columbus Crew× Colorado Rapids | vs | Colorado Rapids |
| 05 de set.21:30 | Austin FC× San Jose Earthquakes | vs | San Jose Earthquakes |
| 05 de set.21:30 | FC Dallas× Sporting Kansas City | vs | Sporting Kansas City |
| 05 de set.21:30 | Seattle Sounders FC× New York Red Bulls | vs | New York Red Bulls |
| 05 de set.22:30 | Real Salt Lake× Los Angeles FC | vs | Los Angeles FC |
| 05 de set.22:30 | LA Galaxy× New England Revolution | vs | New England Revolution |
| 05 de set.23:30 | Portland Timbers× Minnesota United | vs | Minnesota United |
| 05 de set.23:30 | Vancouver Whitecaps× St.Louis City | vs | St.Louis City |
| 09 de set.20:30 | Atlanta United× Orlando City SC | vs | Orlando City SC |
| 09 de set.20:30 | CF Montréal× Charlotte FC | vs | Charlotte FC |
| 09 de set.20:30 | DC United× Columbus Crew | vs | Columbus Crew |
| 09 de set.20:30 | Philadelphia Union× FC Cincinnati | vs | FC Cincinnati |
| 09 de set.20:30 | Toronto FC× Nashville SC | vs | Nashville SC |
| 09 de set.21:00 | New York City FC× New England Revolution | vs | New England Revolution |
| 09 de set.21:30 | Houston Dynamo× Real Salt Lake | vs | Real Salt Lake |
| 09 de set.21:30 | Minnesota United× FC Dallas | vs | FC Dallas |
| 09 de set.21:30 | Austin FC× Colorado Rapids | vs | Colorado Rapids |
| 09 de set.21:30 | Chicago Fire× Inter Miami CF | vs | Inter Miami CF |
| 09 de set.23:30 | Los Angeles FC× New York Red Bulls | vs | New York Red Bulls |
| 09 de set.23:30 | Portland Timbers× St.Louis City | vs | St.Louis City |
| 09 de set.23:30 | San Diego FC× San Jose Earthquakes | vs | San Jose Earthquakes |
| 09 de set.23:30 | Vancouver Whitecaps× LA Galaxy | vs | LA Galaxy |
by 11Group